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A collection of scientific articles about new advances, interesting papers, and interviews for all to digest!
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Blood vessels seem remarkably simple; they are just tubes that carry blood throughout our body. The innermost layer of these vessels, however, is composed of a single, flat layer of specialized endothelial cells called the endothelium. These endothelial cells are incredibly dynamic as they have the capacity to “activate,” growing into new, small blood vessels.…
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The success of nucleoside-modified mRNA vaccines has redefined modern vaccine platform design. These vaccines deliver antigen-encoding mRNA packaged inside lipid nanoparticles (LNPs), generating potent neutralizing antibodies and durable memory B cell responses. One defining feature of mRNA vaccination is its ability to drive strong germinal center (GC) reactions – the specialized structures in lymph nodes where high-affinity antibody-secreting cells are…
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The engineering of chimeric antigen receptor (CAR) T cells has been a significant recent advance in cancer therapy. CAR T cells are manufactured by collecting a patient’s own T cells, engineering these T cells to express a synthetic signaling molecule (the CAR) that specifically redirects the T cell response towards cancer cells, and re-infusing the…
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